ProDots Recombinant Human IL-3 Protein (5 ug)

货号: PRD203-01

反应种属:

Human
Human

库存: 国外现货

规格: 5ug
产品说明书
分享:

价格: ¥ 1333.00

目录价: ¥1333.00

数量
- +
加入购物车
产品介绍商品评论
概述
简介
Supplied as ready-to-use 5 ug protein balls
别名
Hematopoietic growth factor; IL-3MGC79398; interleukin 3 (colony-stimulating factor, multiple); interleukin-3; Mast cell growth factor; mast-cell growth factor; MCGFMGC79399; MULTI-CSF; multilineage-colony-stimulating factor; Multipotential colony-stimulating factor; P-cell stimulating factor; P-cell-stimulating factor
全称
Interleukin 3
反应种属
Human
是否允许进口
允许
是否危险品
非危险品
性能
供应商
R&D Systems
Entrez Gene IDs
3562 (Human); 16187 (Mouse); 24495 (Rat)
内毒素水平
<0.10 EU per 1 μg of the protein by the LAL method.
生物活性
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. Kitamura, T. et al. (1989) J. Cell Physiol. 140:323. The ED50 for this effect is typically 0.02-0.1 ng/mL.
背景
Interleukin-3 (IL-3) is a secreted cytokine that stimulates the proliferation and differentiation of pluripotent hematopoietic stem cells and various lineage-committed progenitors. It also regulates the activation of mature mast cells, basophils, eosinophils, and macrophages. It is produced by activated T cells, thymic epithelial cells, activated mast cells, keratinocytes, neurons, and astrocytes. IL-3 signals through a receptor complex that contains IL-3 R alpha/CD123 and the common beta chain which is also a component of the receptors for IL-5 and GM-CSF. Receptors for IL-3 are present on bone marrow progenitors, macrophages, mast cells, eosinophils, megakaryocytes, basophils, and various myeloid leukemic cells. Human IL-3 does not show activity on mouse cells.
Accession #
N-terminal
Sequence Analysis

Ala20 and Met

预期分子量
15 kDa
SDS-PAGE
14 kDa, reducing conditions
存放说明
4C
纯度
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
参考文献
  • Common beta Chain Receptor Family
  • Cytokines and Receptors in Allergy and Asthma
  • ICC / IHC Images: IL-3
  • Megakaryocytes
  • T Cell Cytokine Signaling

参考图片

1 μg/lane of ProDots® Recombinant Human IL-3 wasresolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized with silver staining, showing a single band at 14 kDa.

ProDots® Recombinant Human IL-3 stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The ED50 for this effect is typically 0.02-0.1 ng/mL.

声明 :本官网所有报价均为常温或者蓝冰运输价格,如有产品需要干冰运输,需另外加收干冰运输费。